Climate Progress: The most popular weed-killer in the United States — and possibly the world — “probably” causes cancer, according to a new report from the World Health Organization (WHO).

Published Thursday in the journal The Lancet Oncology, the report focuses on a chemical called glyphosate, invented by Monsanto back in 1974 as a broad-spectrum herbicide. It’s the active ingredient in Roundup, a popular product used mostly in commercial agriculture production. Roundup is particularly good for genetically modified crops, which can be bred to resist damage from the product while it kills the weeds surrounding it.

In the U.S., glyphosate is not considered carcinogenic. The Environmental Protection Agency’s current position is that “there is inadequate evidence to state whether or not glyphosate has the potential to cause cancer from a lifetime exposure in drinking water.” In the wake of Thursday’s report, however, the EPA said it “would consider” the U.N. agency’s findings.

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