Music: Tigran Hamasyan — ‘The Legend Of The Moon’
Author Archives: Attention to the Unseen
Music: Tigran Hamasyan — ‘Love Song’
Music: Tigran Hamasyan — ‘Mother, Where Are You’
Music: Tigran Hamasyan — ‘The Court Jester’
Music: Tigran Hamasyan — ‘Road Song’ (Froggy’s Session)
Music: Tigran Hamasyan — ‘Some Day My Prince Will Come’
Music: Tigran Hamasyan — ‘What The Waves Brought’
How American doctors are giving their patients cancer
Rita F. Redberg, a cardiologist and Rebecca Smith-Bindman, a radiologist, write: Despite great strides in prevention and treatment, cancer rates remain stubbornly high and may soon surpass heart disease as the leading cause of death in the United States. Increasingly, we and many other experts believe that an important culprit may be our own medical practices: We are silently irradiating ourselves to death.
The use of medical imaging with high-dose radiation — CT scans in particular — has soared in the last 20 years. Our resulting exposure to medical radiation has increased more than sixfold between the 1980s and 2006, according to the National Council on Radiation Protection & Measurements. The radiation doses of CT scans (a series of X-ray images from multiple angles) are 100 to 1,000 times higher than conventional X-rays.
Of course, early diagnosis thanks to medical imaging can be lifesaving. But there is distressingly little evidence of better health outcomes associated with the current high rate of scans. There is, however, evidence of its harms.
The relationship between radiation and the development of cancer is well understood: A single CT scan exposes a patient to the amount of radiation that epidemiologic evidence shows can be cancer-causing. The risks have been demonstrated directly in two large clinical studies in Britain and Australia. In the British study, children exposed to multiple CT scans were found to be three times more likely to develop leukemia and brain cancer. In a 2011 report sponsored by Susan G. Komen, the Institute of Medicine concluded that radiation from medical imaging, and hormone therapy, the use of which has substantially declined in the last decade, were the leading environmental causes of breast cancer, and advised that women reduce their exposure to unnecessary CT scans.
CTs, once rare, are now routine. One in 10 Americans undergo a CT scan every year, and many of them get more than one. This growth is a result of multiple factors, including a desire for early diagnoses, higher quality imaging technology, direct-to-consumer advertising and the financial interests of doctors and imaging centers. CT scanners cost millions of dollars; having made that investment, purchasers are strongly incentivized to use them.
While it is difficult to know how many cancers will result from medical imaging, a 2009 study from the National Cancer Institute estimates that CT scans conducted in 2007 will cause a projected 29,000 excess cancer cases and 14,500 excess deaths over the lifetime of those exposed. Given the many scans performed over the last several years, a reasonable estimate of excess lifetime cancers would be in the hundreds of thousands. According to our calculations, unless we change our current practices, 3 percent to 5 percent of all future cancers may result from exposure to medical imaging. [Continue reading…]
Too much to remember?
Benedict Carey writes: People of a certain age (and we know who we are) don’t spend much leisure time reviewing the research into cognitive performance and aging. The story is grim, for one thing: Memory’s speed and accuracy begin to slip around age 25 and keep on slipping.
The story is familiar, too, for anyone who is over 50 and, having finally learned to live fully in the moment, discovers it’s a senior moment. The finding that the brain slows with age is one of the strongest in all of psychology.
Over the years, some scientists have questioned this dotage curve. But these challenges have had an ornery-old-person slant: that the tests were biased toward the young, for example. Or that older people have learned not to care about clearly trivial things, like memory tests. Or that an older mind must organize information differently from one attached to some 22-year-old who records his every Ultimate Frisbee move on Instagram.
Now comes a new kind of challenge to the evidence of a cognitive decline, from a decidedly digital quarter: data mining, based on theories of information processing. In a paper published in Topics in Cognitive Science, a team of linguistic researchers from the University of Tübingen in Germany used advanced learning models to search enormous databases of words and phrases.
Since educated older people generally know more words than younger people, simply by virtue of having been around longer, the experiment simulates what an older brain has to do to retrieve a word. And when the researchers incorporated that difference into the models, the aging “deficits” largely disappeared.
“What shocked me, to be honest, is that for the first half of the time we were doing this project, I totally bought into the idea of age-related cognitive decline in healthy adults,” the lead author, Michael Ramscar, said by email. But the simulations, he added, “fit so well to human data that it slowly forced me to entertain this idea that I didn’t need to invoke decline at all.” [Continue reading…]
Music: Dhafer Youssef — ‘Les Ondes Orientales’
Whose Holocaust?
The genocidal policies of the Nazis resulted in the deaths of about as many Polish Gentiles as Polish Jews, thus making them co-victims in a Forgotten Holocaust. This Holocaust has been largely ignored because historians who have written on the subject of the Holocaust have chosen to interpret the tragedy in exclusivistic terms — namely, as the most tragic period in the history of the Jewish Diaspora. To them, the Holocaust was unique to the Jews, and they therefore have had little or nothing to say about the nine million Gentiles, including three million Poles, who also perished in the greatest tragedy the world has ever known. — Richard C. Lukas, preface to The Forgotten Holocaust: The Poles under German Occupation 1939-1944
We are surrounded today by fictions about the past, contrary to common sense and to an elementary perception of good and evil. As The Los Angeles Times recently stated, the number of books in various languages which deny that the Holocaust ever took place, that it was invented by Jewish propaganda, has exceeded one hundred. If such an insanity is possible, is a complete loss of memory as a permanent state of mind improbable? And would it not present a danger more grave than genetic engineering or poisoning of the natural environment?
For the poet of the “other Europe” the events embraced by the name of the Holocaust are a reality, so close in time that he cannot hope to liberate himself from their remembrance unless, perhaps, by translating the Psalms of David. He feels anxiety, though, when the meaning of the word Holocaust undergoes gradual modifications, so that the word begins to belong to the history of the Jews exclusively, as if among the victims there were not also millions of Poles, Russians, Ukrainians and prisoners of other nationalities. He feels anxiety, for he senses in this a foreboding of a not distant future when history will be reduced to what appears on television, while the truth, as it is too complicated, will be buried in the archives, if not totally annihilated. — Czeslaw Milosz, 1980
The Polish-American poet John Guzlowski writes: My mother wasn’t an educated woman. She had no college, no high school even. She couldn’t read the books that argue about who was and who was not in the Holocaust.
When I was growing up, she never said she was in the Holocaust. She wasn’t a talker, but she talked a little about what happened to her family. Her mother and sister and the sister’s baby were killed by German Soldiers and Ukrainian neighbors. She had two aunts who died in Auschwitz with their Jewish husbands. My mother spent a couple years in a slave labor camp in Germany. There were Jews and non-Jews in her camp; people suffered and died there. She didn’t talk about any of this much, and when she did she didn’t use the word “Holocaust.”
This changed as she got older. Toward the end of the 1990s, she started talking about how she was in the Holocaust. I think part of this might have come from the fact that people in general, not historians or academics but “just plain folks,” were using the term more often. They had seen Schindler’s List and Life is Beautiful and Holocaust and other films about the Holocaust. I heard her using this word and saying that she was in the Holocaust. She said this to Christians (she was Catholic) and Jews alike. Maybe it was a sort of short hand for her. She was getting older and it was harder for her, I think, to try to explain to people that Polish Catholics also were in death camps and slave labor camps like their Jewish neighbors.
Was my mother right to use this word “Holocaust”? Did she have a right to use this word?
I think she had a right. When my father tried to talk about what happened to my mother during the war, he couldn’t say much. Sometimes, he would start crying, and all he could say then was, “She suffered so much.”
I have an education, and I’ve read about the debate concerning the word “Holocaust.” I think I can lay out some of the arguments from each side in a rudimentary sort of way given the complexity of everything that happened in World War II. One side feels that the Holocaust is what happened to the Jews alone. This side feels that the Nazis and their anti-Semitic allies in all countries worked to eliminate the Jews, and that what happened to the Jews was unique. The other side of the argument has it that Non-Jews by the millions from all of Europe suffered and died alongside the Jews, and that the term Holocaust should apply to all of those who suffered and died in the camps.
So, you ask, what do I think about using the word “Holocaust.” First, I’d have to say that I would never have told my mother that she wasn’t in the Holocaust. I think she had a right to describe her experiences in any way that she saw fit. She was there, she suffered. If she felt she was in the Holocaust, I wouldn’t argue with her.
Second, let me say, that I believe that what happened to Jews was different from what happened to non-Jews. Jews were singled out for immediate destruction. They suffered, they starved, they waited, they died, they waited, they died. Non-Jews who were considered non-Aryan (the Poles, the Italians, the Russians, the Rumanians, the Czechs, and others) were not singled out for immediate destruction. They suffered, they lingered, they starved, they waited, they died, they waited. My father used to talk about the difference between the death camps that the Jews were in and the slave labor camps he was in this way: The Jews, he would say, were in the death camps; he was in the slow-death camps.
To me, it doesn’t seem necessary to spend time discussing the word “Holocaust” and whether it’s applicable to what happened to my parents and other non-Jews.
I think about the Jewish dead and I think about the non-Jewish dead. They are dead.
What I know of hell comes to me primarily from my reading of Dante’s Inferno. In his hell, no one is untouched by pain. Everyone suffers. Some suffer more. Some suffer most. What I know of pain and suffering teaches me that I cannot judge the suffering and pain another feels. I can try to ease that pain and suffering. That is pretty much all I can do.
Let me also say this, I think that all of us who talk about what happened in those dark years of Hitler’s ascendancy and power and the Holocaust and suffering he helped to bring about finally cannot fully understand what happened or what it felt like or what it was like. In this respect, all of us, despite our very best efforts, cannot know what the Holocaust was. We are finally tourists in the kingdom of the Holocaust. We look, we wonder, we cry, we look, we turn away, we look again.
The importance of consilience in science
These are refrains that I and other science communicators have been using over and over again when we turn to analysing debates and discussions based on scientific principles. I think we get torn between remaining true to the philosophical principles by which science is conducted and trying to make those principles familiar to an audience that probably does not understand them.
So let me introduce a concept that is all-too-often overlooked in science discussions, that can actually shed some light deep into the mechanisms of science and explain the anatomy of a scientific debate. It’s the phonically beautiful term ‘consilience’.
Consilience means to use several different lines of inquiry that converge on the same or similar conclusions. The more independent investigations you have that reach the same result, the more confidence you can have that the conclusion is correct. Moreover, if one independent investigation produces a result that is at odds with the consilience of several other investigations, that is an indication that the error is probably in the methods of the adherent investigation, not in the conclusions of the consilience.
Let’s take an example to unpack this concept, an example where I first came across the term and it is a beautiful case of consilience at work. Charles Darwin’s On Origin Of Species is a masterpiece of consilience. Each chapter is a separate line of investigation and, within each chapter there are numerous examples, investigations and experiments that all join together to reach the same conclusion: that life changes through time and that life has evolved on Earth. Take apart On Origin Of Species case by case and no single piece of evidence that Darwin mustered conclusively demonstrates that evolution is true. But add those cases back together and the consilience is clear: evidence from artificial breeding, palaeontology, comparative morphology and a host of other independent lines of investigation combine to confirm the same inescapable conclusion.
That was 1859. Since then yet more investigations have been added to the consilience for evolution. What’s more, these investigations within the biological and geological sciences have been joined with others from physics and chemistry as well as completely new areas of science such as genetics, radiometric dating and molecular biology. Each independent line of investigation builds the consilience that the world and the universe are extremely old and that life has evolved through unfathomable durations of time here on our home planet.
So, when a new line of investigation comes along claiming evidence and conclusions contrary to evolution, how can that be accommodated within the consilience? How does it relate to so many independent strains conjoined by a similar conclusion at odds with the newcomer? Can one piece of evidence overthrow such a huge body of work?
Such is the thinking of those pesky creationists who regularly come up with “Ah-Ha!” and “Gotcha!” factoids that apparently overturn, not just evolution, but the whole consilience of science. [Continue reading…]
Music: Bugge Wesseltoft & Sidsel Endresen — ‘You Might Say’
Music: Nils Petter Molvaer — ‘Only These Things Count’
Vocals: Sidsel Endresen
Stephen Hawking: ‘There are no black holes’
Nature reports: Most physicists foolhardy enough to write a paper claiming that “there are no black holes” — at least not in the sense we usually imagine — would probably be dismissed as cranks. But when the call to redefine these cosmic crunchers comes from Stephen Hawking, it’s worth taking notice. In a paper posted online, the physicist, based at the University of Cambridge, UK, and one of the creators of modern black-hole theory, does away with the notion of an event horizon, the invisible boundary thought to shroud every black hole, beyond which nothing, not even light, can escape.
In its stead, Hawking’s radical proposal is a much more benign “apparent horizon”, which only temporarily holds matter and energy prisoner before eventually releasing them, albeit in a more garbled form.
“There is no escape from a black hole in classical theory,” Hawking told Nature. Quantum theory, however, “enables energy and information to escape from a black hole”. A full explanation of the process, the physicist admits, would require a theory that successfully merges gravity with the other fundamental forces of nature. But that is a goal that has eluded physicists for nearly a century. “The correct treatment,” Hawking says, “remains a mystery.”
Hawking posted his paper on the arXiv preprint server on 22 January. He titled it, whimsically, ‘Information preservation and weather forecasting for black holes’, and it has yet to pass peer review. The paper was based on a talk he gave via Skype at a meeting at the Kavli Institute for Theoretical Physics in Santa Barbara, California, in August 2013 (watch video of the talk). [Continue reading…]
Music: Dhafer Youssef — ‘Aya 1984’ (live)
Music: Dhafer Youssef — ‘Byzance’
A new theory about the origin of life
Evolution explains how life changes, but it doesn’t explain how it came into existence. A young physicist at MIT has now come up with a mathematical formula which suggests that given the right set of conditions, the emergence of living forms is not merely possible; it almost seems inevitable.
Let there be light, shining on atoms, and there will eventually be life.
Quanta magazine: Why does life exist?
Popular hypotheses credit a primordial soup, a bolt of lightning and a colossal stroke of luck. But if a provocative new theory is correct, luck may have little to do with it. Instead, according to the physicist proposing the idea, the origin and subsequent evolution of life follow from the fundamental laws of nature and “should be as unsurprising as rocks rolling downhill.”
From the standpoint of physics, there is one essential difference between living things and inanimate clumps of carbon atoms: The former tend to be much better at capturing energy from their environment and dissipating that energy as heat. Jeremy England, a 31-year-old assistant professor at the Massachusetts Institute of Technology, has derived a mathematical formula that he believes explains this capacity. The formula, based on established physics, indicates that when a group of atoms is driven by an external source of energy (like the sun or chemical fuel) and surrounded by a heat bath (like the ocean or atmosphere), it will often gradually restructure itself in order to dissipate increasingly more energy. This could mean that under certain conditions, matter inexorably acquires the key physical attribute associated with life.
“You start with a random clump of atoms, and if you shine light on it for long enough, it should not be so surprising that you get a plant,” England said.
England’s theory is meant to underlie, rather than replace, Darwin’s theory of evolution by natural selection, which provides a powerful description of life at the level of genes and populations. “I am certainly not saying that Darwinian ideas are wrong,” he explained. “On the contrary, I am just saying that from the perspective of the physics, you might call Darwinian evolution a special case of a more general phenomenon.”
His idea, detailed in a recent paper and further elaborated in a talk he is delivering at universities around the world, has sparked controversy among his colleagues, who see it as either tenuous or a potential breakthrough, or both.
England has taken “a very brave and very important step,” said Alexander Grosberg, a professor of physics at New York University who has followed England’s work since its early stages. The “big hope” is that he has identified the underlying physical principle driving the origin and evolution of life, Grosberg said.
“Jeremy is just about the brightest young scientist I ever came across,” said Attila Szabo, a biophysicist in the Laboratory of Chemical Physics at the National Institutes of Health who corresponded with England about his theory after meeting him at a conference. “I was struck by the originality of the ideas.”
Others, such as Eugene Shakhnovich, a professor of chemistry, chemical biology and biophysics at Harvard University, are not convinced. “Jeremy’s ideas are interesting and potentially promising, but at this point are extremely speculative, especially as applied to life phenomena,” Shakhnovich said.
England’s theoretical results are generally considered valid. It is his interpretation — that his formula represents the driving force behind a class of phenomena in nature that includes life — that remains unproven. But already, there are ideas about how to test that interpretation in the lab. [Continue reading…]
